PENGARUH PRA-PERLAKUAN DENTIN DENGAN FLAVONOID DAN AGEN REMINERALISASI TERHADAP KUAT REKAT DENTIN: TELAAH PUSTAKA
DOI:
https://doi.org/10.21776/ub.eprodenta.2024.008.01.3Keywords:
Flavonoid, Agen Remineralisasi, Kuat Rekat Dentin, Caries Affected DentinAbstract
Latar Belakang: Ketahanan kuat rekat resin komposit-dentin yang karies menjadi permasalahan dikarenakan terjadi
demineralisasi parsial oleh enzim kolagenolitik yaitu matrix metalloproteinases (MMPs). Enzim MMPs dapat
mengakibatkan degradasi matriks kolagen pada lapisan hibrida. Maka dilakukan pra-perlakuan dentin menggunakan
agen pengikat silang eksogen berupa larutan flavonoid sebagai inhibitor MMPs. Selain itu, dapat juga menggunakan
agen remineralisasi pada dentin yang karies sebagai pra-perlakuan untuk meningkatkan kuat rekatnya. Tujuan:
Mengevaluasi pengaruh pra-perlakuan dentin menggunakan berbagai senyawa flavonoid, agen remineralisasi
maupun kombinasi keduanya terhadap kuat rekat resin komposit-dentin. Metode: Gigi premolar atau molar pada
permukaan dentin diaplikaskan pra-perlakuan (flavonoid, agen remineralisasi dan kombinasi) selama 1 menit
sebelum aplikasi material adhesif lalu dievaluasi dengan uji kuat rekat tarik mikro. Pembahasan: Peningkatan kuat
rekat resin komposit-dentin pada uji kuat rekat Tarik mikro kelompok yang diberikan pra-perlakukan dentin
dibandingkan tanpa pra-perlakuan karena senyawa flavonoid mengikat kolagen fibril agar tidak dapat terdegradasi
oleh enzim MMPs. Lalu agen remineralisasi juga menginduksi mineral apatit baru yang meningkatkan kuat rekat
dentin. Kesimpulan: Pengaruh pra-perlakuan dentin menggunakan berbagai senyawa flavonoid dan agen
remineralisasi dapat meningkatkan kuat rekat resin komposit-dentin yang telah yang mengalami karies (caries
affected dentin/CAD).
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